A UPS cargo airplane crashed Tuesday in Louisville, Kentucky, killing multiple people and introducing potential delays for packages flowing through the carrier’s main air hub.

At least nine people died in the incident near the Louisville Muhammad Ali International Airport, "with the possibility of more," Kentucky Gov. Andy Beshear said Wednesday morning on X.

The MD-11 plane departing from Louisville had three crewmembers onboard and was destined for Honolulu prior to its crash, UPS said in a statement.

"Our heartfelt thoughts are with everyone involved," the company said. "UPS is committed to the safety of our employees, our customers and the communities we serve. This is particularly true in Louisville, home to our airline and thousands of UPSers."

UPS said it would halt package sorting operations at its Worldport facility in Louisville on Tuesday night as a result of the crash. In an update Wednesday morning, the carrier added that its Second Day Air sort at the facility has been canceled for the day.

Worldport, UPS' top air hub and largest package handling facility, sees 300 flights daily and sorts over 400,000 packages an hour, according to the company's website. A UPS service alert said scheduled delivery times for air and international packages may be affected due to the situation.

"Contingency plans are in place to help ensure that shipments arrive at their final destinations as quickly as conditions permit," the alert said, without elaborating on the specifics of the contingencies.